Thermo Fisher Scientific SRSF2 Polyclonal Antibody
SRSF2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ELISA에 사용 가능. Human, Mouse, Rat에 반응하며 Affinity Chromatography로 정제됨. PBS/glycerol buffer에 보관되며 -20°C에서 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human SRSF2 (NP_001182356.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.42 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2806360 |
Product Specific Information
Immunogen sequence:
MSYGRPPPDV EGMTSLKVDN LTYRTSPDTL RRVFEKYGRV GDVYIPRDRY TKESRGFAFV RFHDKRDAED AMDAMDGAVL DGRELRVQMA RYGRPPDSHH
Positive Samples: Mouse lung
Cellular Location: Nucleus, Nucleus speckle, nucleoplasm
Target Information
The protein encoded by SC35 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which are components of the spliceosome. These proteins contain an RNA recognition motif (RRM) for RNA binding and an RS domain for protein interactions. The RS domain, rich in serine and arginine residues, facilitates interactions among SR splicing factors. SR proteins are critical for mRNA splicing, export from the nucleus, and translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been identified for SC35, along with a pseudogene on chromosome 11.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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