Thermo Fisher Scientific Defensin beta 2/DEFB2/HBD-2 Polyclonal Antibody
Mouse Defensin beta 2에 특이적인 Rabbit Polyclonal Antibody로, IHC, ICC/IF, ELISA 등 다양한 응용 가능. KLH 결합 합성 펩타이드(aa 21-71)로부터 유도된 면역원 사용. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse Defensin Beta 2, amino acids 21–71 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Defensins (alpha and beta) are cationic peptides with broad-spectrum antimicrobial activity and are key components of the innate immune system. Alpha-defensins differ from beta-defensins by the pairing of their three disulfide bonds. Six human beta-defensins have been identified: BD-1, BD-2, BD-3, BD-4, BD-5, and BD-6. Beta-defensins are expressed on certain leukocytes and epithelial surfaces. Beyond antimicrobial activity, they serve as chemoattractants for immature dendritic cells and memory T cells. Beta-defensins are expressed as C-terminal portions of precursors and released via proteolytic cleavage. They contain a six-cysteine motif forming three intra-molecular disulfide bonds.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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