Thermo Fisher Scientific Phospho-alpha Adducin (Thr445) Polyclonal Antibody
Phospho-alpha Adducin (Thr445) 폴리클로날 항체로 인간, 생쥐, 랫트 시료에 반응합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며 Protein A로 정제된 고순도 항체입니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Thr445 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein composed of related subunits produced from distinct genes but sharing similar structures. Alpha- and beta-adducins include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed, whereas beta-adducin is highly expressed in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and serves as a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, though not all variants have been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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