Thermo Fisher Scientific Muromonab Chimeric Recombinant Rabbit Monoclonal Antibody (OKT-3 (muromonab))
인간 CD3 복합체의 epsilon 서브유닛을 인식하는 재조합 토끼 단일클론 항체. ICC/IF 및 유세포분석에 사용 가능. 1 mg/mL 농도의 액상 형태로 제공되며, 단백질 A로 정제됨. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | OKT-3 (muromonab) |
| Immunogen | Human peripheral E+ cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074219 |
Product Specific Information
Specificity: Epitope on the epsilon-subunit within the human CD3 complex.
Target Information
Muromonab is a murine monoclonal antibody specific to CD3 T-cell lymphocyte antigens. It is a purified murine (mouse) monoclonal antibody directed against the CD3 (T3) receptor on the surface of human T-cells (T-lymphocytes), cultured using the murine ascites method. Muromonab is 93% monomeric immune globulin G type 2a (IgG2a). It binds to the T-cell surface glycoprotein CD3 epsilon chain and induces Fc-mediated apoptosis, antibody-mediated cytotoxicity, and complement-dependent cytotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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