Thermo Fisher Scientific CD200R Chimeric Recombinant Rabbit Monoclonal Antibody (OX108)
인간 CD200R을 인식하는 재조합 토끼 단클론 항체(OX108)로, Flow Cytometry에 적합합니다. HEK293 세포에서 발현되었으며 Protein A로 정제되었습니다. 액상 형태로 제공되며, PBS에 0.02% ProClin 300이 포함되어 있습니다. 연구용으로만 사용 가능합니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | OX108 |
| Immunogen | Recombinant protein - hCD200RCD4d3+4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074215 |
Product Specific Information
Specificity: Recognizes human CD200R, a receptor for the CD200/OX2.
Target Information
CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein, and both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. CD200R is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal.
In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutrophils but also by other leucocytes including T-lymphocytes and mast cells. Further mouse studies of a gene related to CD200R suggest that the receptor may control myeloid function in a tissue-specific manner.
Alternative splicing of CD200R results in multiple transcript variants. Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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