Thermo Fisher Scientific CD200R Recombinant Mouse Monoclonal Antibody (OX108)
인간 CD200R을 특이적으로 인식하는 재조합 마우스 단클론 항체(OX108). Flow cytometry 등 다양한 분석에 사용 가능. HEK293 세포에서 발현된 IgG1, kappa 형 항체로 Protein A로 정제됨. 연구용으로만 사용.
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Thermo Fisher Scientific CD200R Recombinant Mouse Monoclonal Antibody (OX108)
Applications
- Flow Cytometry (Flow)
Tested Dilution: Assay-dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | OX108 |
| Immunogen | Recombinant protein - hCD200RCD4d3+4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074214 |
Product Specific Information
Specificity: Recognizes human CD200R, a receptor for the CD200/OX2.
Target Information
CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein. Both receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains.
CD200R is restricted to surfaces of myeloid lineage cells and may function as a myeloid downregulatory signal.
In mouse, CD200R is expressed primarily by peripheral blood monocytes and neutrophils, as well as other leukocytes including T-lymphocytes and mast cells.
Studies suggest CD200R may control myeloid function in a tissue-specific manner.
Alternative splicing of CD200R results in multiple transcript variants.
Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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