Thermo Fisher Scientific NAG-1 Polyclonal Antibody
Thermo Fisher Scientific의 NAG-1 Polyclonal Antibody는 인간 및 생쥐 시료에서 NAG-1 단백질을 검출하기 위한 고순도 Protein A 정제 항체입니다. WB, ELISA, IP 등 다양한 응용에 적합하며, 안정적인 액상 형태로 제공되어 장기 보관이 가능합니다.
- 카탈로그번호
- 209-401-B88x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NAG-1 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:500 |
| Immunoprecipitation (IP) | 1:800–1:1,500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | MBP-tagged recombinant human NAG-1 protein produced in E. coli; cross-reactivity to MBP removed via cross-adsorption chromatography |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.37 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This antibody reacts with endogenous NAG-1 protein from human tissues. BLAST analysis indicates reactivity with NAG-1 from human and chimpanzee (100% and 98% homology, respectively), macaque (94% homology), and mouse and rat (70% homology). Cross-reactivity with NAG-1 from other species has not been determined.
Target Information
GDF-15 belongs to the TGF-beta cytokine family, which plays an important role in prenatal development, postnatal growth, and tissue remodeling and maintenance. GDF-15 is expressed predominantly in the placenta and, to a lesser extent, in various other tissues. Its presence in amniotic fluid and elevated levels in pregnant women’s sera suggest involvement in gestation and embryonic development. GDF-15 generally exhibits tumor suppressive activities and is a major factor produced in response to p53 pathway activation. Serum levels of GDF-15 correlate positively with progression of several tumor types, including colorectal, pancreatic, and prostate cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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