
Thermo Fisher Scientific GSK3B Recombinant Superclonal Antibody (1HCLC)
GSK3B 단백질을 표적으로 하는 Thermo Fisher Scientific의 Recombinant Superclonal 항체입니다. Western blot 및 ICC/IF에 적합하며, 높은 특이성과 재현성을 제공합니다. 인간, 마우스, 영장류 반응성이 있으며, 재조합 시스템으로 일관된 품질을 보장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5–1 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 1HCLC |
| Immunogen | Recombinant protein corresponding to amino acids 317–433 of human GSK3 beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532582 |
Product Specific Information
This antibody is predicted to react with equine, mouse, rabbit, and rat based on sequence homology.
Recombinant rabbit Superclonal™ antibodies from Thermo Fisher Scientific combine multiple recombinant monoclonal antibodies, offering both the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with the consistency of recombinant production.
They recognize multiple epitope sites, ensuring higher detection sensitivity for low-abundance targets. Each lot is produced with the same known mixture of light and heavy chains, minimizing biological variability.
Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody” without change in performance.
Target Information
GSK3B (Glycogen Synthase Kinase 3 Beta) is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal development, and body pattern formation.
It negatively regulates glucose homeostasis and participates in pathways related to energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptosis.
GSK3B is a key component of the Wnt/β-catenin signaling pathway, inhibiting Wnt signaling by mediating β-catenin degradation. It also plays roles in Hedgehog, Notch, and insulin signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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