Thermo Fisher Scientific NAGA Monoclonal Antibody (OTI6F3), TrueMAB
인간 NAGA 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화되었습니다. HEK293T 세포에서 발현된 full-length recombinant NAGA를 면역원으로 사용하였으며, 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA811239
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F3 |
| Immunogen | Full-length human recombinant NAGA protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 amino acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It may exist as a homodimer and plays a critical role in glycolipid breakdown.
The NAGA gene encodes a lysosomal enzyme that cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates and maps to human chromosome 22q13.2.
Defects in NAGA cause autosomal recessive disorders known as Schindler disease (types I, II, and III) or NAGA deficiency, characterized by varying degrees of neurological manifestations. Type I is the most severe, type III has mild-to-moderate effects, and type II (Kanzaki disease) presents with mild intellectual impairment and angiokeratoma corporis diffusum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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