Thermo Fisher Scientific NAGA Monoclonal Antibody (OTI6F3), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Target Information

NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 amino acid lysosomal protein belonging to the glycosyl hydrolase 27 family. It may exist as a homodimer and plays a critical role in glycolipid breakdown.
The NAGA gene encodes a lysosomal enzyme that cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates and maps to human chromosome 22q13.2.
Defects in NAGA cause autosomal recessive disorders known as Schindler disease (types I, II, and III) or NAGA deficiency, characterized by varying degrees of neurological manifestations. Type I is the most severe, type III has mild-to-moderate effects, and type II (Kanzaki disease) presents with mild intellectual impairment and angiokeratoma corporis diffusum.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.