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Thermo Fisher Scientific SIGLEC5/SIGLEC14 Monoclonal Antibody (1A5), PE
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Thermo Fisher Scientific SIGLEC5/SIGLEC14 Monoclonal Antibody (1A5), PE

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인간 Siglec-5/CD170 단백질을 인식하는 단클론 항체로, Flow Cytometry에 적합합니다. PE 형광체로 결합되어 있으며, 단백질 A로 정제되었습니다. 4°C에서 보관하며, 재구성 후 사용 가능합니다. 연구용으로만 사용됩니다.

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마지막 업데이트 2025. 08. 03. 오전 07:26
Thermo Fisher Scientific MA528139 SIGLEC5/SIGLEC14 Monoclonal Antibody (1A5), PE 100 tests pk판매 단위 pk ·
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761,500원VAT 포함 837,650원

Thermo Fisher Scientific · Thermo Fisher Scientific SIGLEC5/SIGLEC14 Monoclonal Antibody (1A5), PE

Applications

  • Flow Cytometry (Flow): Tested dilution 10 µL

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone 1A5
Immunogen Siglec-5-Fc protein, consisting of the full-length extracellular region of human Siglec-5 fused with the Fc region of human IgG1
Conjugate PE (R-Phycoerythrin)
Excitation / Emission Max 565 / 576 nm
Form Lyophilized
Concentration 1 mg/mL
Purification Protein A
Storage Buffer PBS with 5% sucrose, 1% BSA
Contains 0.09% sodium azide
Storage Conditions 4°C, store in dark, DO NOT FREEZE
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2745121

Additional Formats

  • Unconjugated (Cat. No. MA5-28140)
  • FITC (Cat. No. MA5-28138)
  • Custom conjugation available upon request

Product Specific Information

This antibody recognizes human Siglec-5 (Sialic acid-binding Ig-like lectin 5), also known as CD170. It is a sialic acid-binding lectin and member of the Ig superfamily, expressed by dendritic cells, activated macrophages, neutrophils, and cells of the monocyte/myeloid lineage.
Reconstitute with 1.0 mg/mL distilled water before use.

Target Information

SIGLEC5 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins contain structural motifs in the immunoglobulin-like domains and sialic acid recognition sites in the first Ig V set domain. The protein belongs to the CD33-related Siglec subset and inhibits activation of monocytes, macrophages, and neutrophils. Binding of group B Streptococcus (GBS) to this protein contributes to GBS immune evasion.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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