
Thermo Fisher Scientific SIGLEC5/SIGLEC14 Monoclonal Antibody (1A5), PE
인간 Siglec-5/CD170 단백질을 인식하는 단클론 항체로, Flow Cytometry에 적합합니다. PE 형광체로 결합되어 있으며, 단백질 A로 정제되었습니다. 4°C에서 보관하며, 재구성 후 사용 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Flow Cytometry (Flow): Tested dilution 10 µL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A5 |
| Immunogen | Siglec-5-Fc protein, consisting of the full-length extracellular region of human Siglec-5 fused with the Fc region of human IgG1 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 5% sucrose, 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745121 |
Additional Formats
- Unconjugated (Cat. No. MA5-28140)
- FITC (Cat. No. MA5-28138)
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes human Siglec-5 (Sialic acid-binding Ig-like lectin 5), also known as CD170. It is a sialic acid-binding lectin and member of the Ig superfamily, expressed by dendritic cells, activated macrophages, neutrophils, and cells of the monocyte/myeloid lineage.
Reconstitute with 1.0 mg/mL distilled water before use.
Target Information
SIGLEC5 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins contain structural motifs in the immunoglobulin-like domains and sialic acid recognition sites in the first Ig V set domain. The protein belongs to the CD33-related Siglec subset and inhibits activation of monocytes, macrophages, and neutrophils. Binding of group B Streptococcus (GBS) to this protein contributes to GBS immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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