Thermo Fisher Scientific SIGLEC5/SIGLEC14 Monoclonal Antibody (1A5)
인간 Siglec-5/Siglec-14 단백질을 인식하는 마우스 단클론 항체. ICC, Flow Cytometry, ELISA, IP 등에 사용 가능. 비결합형 액상 형태로 제공되며 1 mg/mL 농도. 단백질 A로 정제되어 높은 특이성과 재현성을 제공.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SIGLEC5/SIGLEC14 Monoclonal Antibody (1A5)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| Flow Cytometry (Flow) | 1:25–1:200 | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
| Functional Assay | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A5 |
| Immunogen | Siglec-5-Fc protein, consisting of the full-length extracellular region of human Siglec-5, fused with the Fc region of human IgG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745122 |
Additional Formats
Product Specific Information
This antibody recognizes human Siglec-5 (Sialic acid-binding Ig-like lectin 5), also known as CD170. It is a sialic acid-binding Ig-like lectin and member of the Ig superfamily, expressed by dendritic cells (DCs), activated macrophages, neutrophils, and cells of the monocyte/myeloid lineage.
Target Information
SIGLEC5 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein belongs to the CD33-related subset of Siglecs and inhibits activation of several cell types, including monocytes, macrophages, and neutrophils. Binding of group B Streptococcus (GBS) to this protein contributes to GBS immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.