Thermo Fisher Scientific PDIA6 Polyclonal Antibody
Thermo Fisher Scientific의 PDIA6 폴리클로날 항체는 인간 P5 단백질을 검출하기 위한 연구용 항체로, WB 및 ICC/IF에 적합합니다. Rabbit IgG 기반 비결합형 항체로, ER 내 PDI 유사 단백질 연구에 활용됩니다. -20°C에서 보관하며, 인간 및 돼지 시료에 반응합니다.
- 카탈로그번호
- PA3008
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:250 | View 4 publications |
| Immunocytochemistry (ICC/IF) | 1:250 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues D(476) I D L S D V E L D D L G K D E L(492) of human P5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2161009 |
Product Specific Information
PA3-008 detects P5 protein in human samples.
It has been successfully used in Western blot procedures, detecting an approximately 50 kDa protein representing P5 in human fibrosarcoma HT1080 cell lysate.
The immunogen is a synthetic peptide corresponding to residues D(476)–E(492) of human P5 (Cat. # PEP-224), available for neutralization and control experiments.
Target Information
P5 is a novel human protein with peptide-binding and chaperone activity specific to certain proteins.
It shares structural similarities with PDI, an important ER protein, and contains the ER retention signal KDEL.
P5 includes two CXXC-like motifs responsible for oxidoreductase activity, located at both termini.
Studies indicate the N-terminal CXXC motif plays a more significant role in isomerase activity.
Unlike most PDI-like proteins, P5 is not stress-inducible.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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