Thermo Fisher Scientific ERp57 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunohistochemistry (Frozen) (IHC (F))

1:200

-

Immunocytochemistry (ICC/IF)

1:250

View 1 publication 1 publication

Flow Cytometry (Flow)

-

View 1 publication 1 publication

Immunoprecipitation (IP)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues I(490) Q E E K P K K K K K A Q E D L(505) of human ERp57. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ERp57,uniProtId:P30101-1,ncbiNodeId:9606,antigenRange:491-505,antigenLength:505,antigenImageFileName:PA3-009_ERp57_P30101-1_Rabbit.svg,antigenImageFileNamePDP:PA3-009_ERp57_P30101-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

0.01% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2160851

Product Specific Information

PA3-009 detects ERp57 protein in human samples.

PA3-009 has successfully been used in Western blot and immunofluorescence procedures. By Western blot, this antibody detects a 57 kDa protein representing ERp57 in rat liver homogenate.

The PA3-009 immunogen is a synthetic peptide corresponding to residues I(490) Q E E K P K K K K K A Q E D L(505) of human ERp57. This peptide (Cat. # PEP-225) is available for use in neutralization and control experiments.

Target Information

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.