Thermo Fisher Scientific Phospho-ATP1A1 (Tyr260) Polyclonal Antibody
ATP1A1 단백질의 Tyr260 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot 및 IHC(P) 검증 완료. 인간, 마우스, 랫트 반응성. PBS 기반 용액 형태로 제공되며 -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ATP1A1 (Accession P05023), corresponding to amino acid residues around phosphorylated Tyr260 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816898 |
Product Specific Information
This antibody detects endogenous levels of ATP1A1 only when phosphorylated at Tyr260.
Target Information
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, specifically the Na⁺/K⁺-ATPases subfamily. Na⁺/K⁺-ATPase is an integral membrane protein responsible for establishing and maintaining electrochemical gradients of sodium and potassium ions across the plasma membrane. These gradients are essential for osmoregulation, sodium-coupled transport of various molecules, and electrical excitability of nerve and muscle cells. The enzyme consists of two subunits: a large catalytic alpha subunit and a smaller glycoprotein beta subunit. This gene encodes the alpha 1 subunit, and multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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