Thermo Fisher Scientific SAR1B Polyclonal Antibody
SAR1B 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF 등에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity chromatography 정제 및 1 mg/mL 농도. 연구용으로 적합하며 -20°C에서 보관.
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Thermo Fisher Scientific SAR1B Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SAR1B (Accession Q9Y6B6), corresponding to amino acid residues L118–L168 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851056 |
Product Specific Information
Antibody detects endogenous levels of total SAR1B.
Target Information
The SAR1B protein is a small GTPase that functions as a homodimer. It is activated by the guanine nucleotide exchange factor PREB and plays a role in protein transport from the endoplasmic reticulum to the Golgi apparatus. SAR1B is a component of the COPII coat complex. Mutations in this gene are associated with chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been identified.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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