Thermo Fisher Scientific DARPP-32 Polyclonal Antibody
DARPP-32 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Mouse와 Rat에 반응하며 WB, IHC, ICC 등 다양한 응용에 적합. 고순도 항원 친화 크로마토그래피로 정제된 액상 제품으로 안정적인 장기 보관 가능.
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Thermo Fisher Scientific DARPP-32 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | View publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 | View publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of mouse DARPP-32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.27 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792924 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (86%).
- Positive control: mouse brain, rat brain.
- Centrifuge briefly prior to opening the vial.
Target Information
DARPP-32 (Dopamine- and AMP-regulated phosphoprotein, 32 kDa) is associated with dopaminoceptive neurons.
When phosphorylated on Thr34, it inhibits Protein Phosphatase I; when phosphorylated on Thr75, it inhibits PKA.
Phosphorylation of DARPP-32 plays a critical role in dopaminergic neurotransmission and is implicated in the actions of alcohol, caffeine, and Prozac®.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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