Thermo Fisher Scientific CRP Polyclonal Antibody
인간 CRP 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ELISA에 적합하며, 항원 친화 크로마토그래피로 정제됨. PBS 완충액에 0.01% sodium azide 포함, 4°C 단기 또는 -20°C 장기 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| ELISA | 0.01–0.1 µg/mL |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of human CRP protein (amino acids 42–49) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: CRP full length recombinant protein
- Cellular location: Cytoplasmic
Target Information
C-reactive protein (CRP) is a major cyclic, pentameric acute-phase protein composed of five identical, noncovalently bound, nonglycosylated subunits of 206 amino acids each (~24 kDa). It is synthesized in the liver, and plasma levels increase markedly during inflammation. CRP functions as an initiator of the classical complement cascade, binds to nuclear components such as chromatin and histones, and plays a key role in innate immunity. It mediates opsonic activity, activates monocytes/macrophages, and acts as a scavenger during cell necrosis. Elevated basal levels of CRP are associated with increased risk of hypertension and cardiovascular disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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