Thermo Fisher Scientific CD19 Monoclonal Antibody (SJ25C1), eFluor 450, eBioscience
인간 CD19를 인식하는 SJ25C1 단클론 항체로, eFluor 450 형광 표지된 유세포분석용 항체입니다. B세포 발현 분석에 적합하며, 405 nm 레이저로 여기됩니다. 액상 형태로 4°C 보관하며, 암조건에서 냉장 보관이 필요합니다.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD19 Monoclonal Antibody (SJ25C1), eFluor 450, eBioscience
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Flow Cytometry (Flow) | 5 µL (0.125 µg)/test | View 13 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), eFluor™ 450, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SJ25C1 |
| Conjugate | eFluor™ 450 |
| Excitation / Emission Max | 405 / 445 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Storage conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping conditions | Wet ice |
| RRID | AB_11218875 |
Additional Available Formats
- Alexa Fluor 488
- Alexa Fluor 532
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 395
- Brilliant UV 496
- Brilliant UV 615
- Brilliant UV 737
- Brilliant UV 805
- Brilliant Violet 605
- Brilliant Violet 650
- eFluor 506
- NovaFluor Blue 610-70S
- NovaFluor Blue 660-120S
- NovaFluor Blue 690
- NovaFluor Red 685
- NovaFluor Red 725
- NovaFluor Red 755
- NovaFluor Yellow 590
- NovaFluor Yellow 610
- NovaFluor Yellow 690
- NovaFluor Yellow 755
- PE
- PE-Cyanine5.5
- PE-Cyanine7
- PE-eFluor 610
- PerCP-Cyanine5.5
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 600
- Super Bright 645
- Super Bright 702
- Super Bright 780
- Request custom conjugation
Product Specific Information
The SJ25C1 monoclonal antibody reacts with human CD19, a 95 kDa transmembrane glycoprotein expressed by B cells during all stages of development except terminally differentiated plasma cells. Follicular dendritic cells also express CD19. CD19 forms a complex with CD21, CD81, Leu13, and MHC class II, which associates with the BCR. Signaling through CD19 induces tyrosine phosphorylation, calcium flux, and proliferation of B cells. The SJ25C1 and HIB19 antibodies recognize overlapping epitopes.
Applications Reported: Flow cytometric analysis.
Applications Tested: Pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. Recommended use: 5 µL (0.125 µg) per test in 100 µL final volume. Cell number range: 10⁵–10⁸ cells/test.
Fluorochrome Information:
eFluor® 450 is an alternative to Pacific Blue®. It emits at 445 nm and is excited with a 405 nm violet laser. Ensure your instrument supports this fluorochrome.
- Excitation: 405 nm
- Emission: 445 nm
- Laser: Violet
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD19 is a member of the immunoglobulin superfamily with two Ig-like domains. It is expressed on 100% of peripheral B cells and may also appear on certain myeloid leukemia cells. CD19 functions as a key regulator of normal and malignant B cell proliferation, serving as a co-receptor that lowers the activation threshold for antigen receptor signaling. Mutations in CD19 can lead to hypogammaglobulinemia, whereas overexpression may cause B cell hyperactivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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