Thermo Fisher Scientific BDNF Polyclonal Antibody
BDNF 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트에 반응하며, 동결 건조 형태로 제공됩니다. 신경세포 생존 및 분화 연구에 유용한 연구용 항체입니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 2 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:1,000 | - |
| Inhibition Assays (IA) | 1:10–1:50 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human BDNF (aa 129–247) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | -20 °C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1070634 |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material. After reconstitution, store aliquots at -20 °C for higher stability, or at 4 °C with an antibacterial agent. Avoid repetitive freeze/thaw cycles. Glycerol (1:1) may be added for additional stability.
Target Information
BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family. It is synthesized as pre-proBDNF, then processed to proBDNF and mature BDNF (14 kDa). Both pro- and mature forms are biologically active and secreted in synaptic vesicles.
BDNF is widely expressed in the central nervous system and acts via TrkB and p75-NTR receptors, promoting neuronal survival, differentiation, and synaptic regulation. It plays a key role in memory formation and is implicated in neurodegenerative diseases such as Alzheimer’s and Huntington’s, as well as in mood disorder regulation.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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