Thermo Fisher Scientific GDNF Polyclonal Antibody
GDNF 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC에 사용 가능. Human, Mouse, Rat 반응성. 동결건조 형태로 제공되며, 재구성 후 안정성을 위해 -20°C 보관 권장. 신경세포 생존 관련 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human GDNF (aa 78–211) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1074601 |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
After reconstitution, keep aliquots at -20°C for higher stability, and at 4°C with an appropriate antibacterial agent.
Glycerol (1:1) may be added for additional stability. Avoid repetitive freeze/thaw cycles.
Target Information
GDNF (Glial cell line-derived neurotrophic factor) is a glycosylated, disulfide-bonded homodimer molecule.
It was first identified as a potent survival factor for midbrain dopaminergic neurons and shown to rescue these neurons in animal models of Parkinson’s disease.
GDNF is about 100 times more efficient as a survival factor for spinal motor neurons than neurotrophins.
It enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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