Thermo Fisher Scientific CD74 Monoclonal Antibody (1B8), FITC
FITC로 표지된 CD74 단클론 항체로 인간 시료에 반응하며 WB와 ICC/IF에 사용 가능. 단백질 G로 정제된 액상 형태로 4°C 암소 보관. 형광 최대값 498/517nm, 보존제 없음. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD74 Monoclonal Antibody (1B8), FITC
Thermo Fisher Scientific CD74 Monoclonal Antibody (1B8), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B8 |
| Immunogen | Human CD74 invariant chain synthetic peptide |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.1 mM sodium bicarbonate/PBS, pH 7.4, with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931833 |
Additional Formats
- APC: MA5-45378
- PerCP: MA5-45380
- Custom conjugation available upon request
Product Specific Information
A 1:1,000 dilution of MA5-45379 was sufficient for detection of CD74 in 15 µg of B-Cell Lymphoma cell line Raji by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.
Detects approximately 33 kDa protein.
Target Information
HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and a 27 kDa beta chain (DRB).
The alpha chain gene contains 5 exons:
- Exon 1 encodes the leader peptide
- Exons 2 and 3 encode the extracellular domains
- Exon 4 encodes the transmembrane domain and cytoplasmic tail
DRA acts as the sole alpha chain for DRB1, DRB3, DRB4, and DRB5 and lacks polymorphisms in the peptide-binding region.
HLA-DR is expressed primarily on antigen-presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells, and activated T lymphocytes.
It plays a critical role in the initiation of immune responses by presenting processed peptides to T-helper cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.