Thermo Fisher Scientific Lysine Acetylated Polyclonal Antibody, Biotin
Biotin conjugated polyclonal antibody recognizing acetylated lysine residues. Suitable for Western blot applications. Affinity-purified from rabbit serum. Stable in glycerol-containing buffer; store at -20°C. For research use only.
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Thermo Fisher Scientific Lysine Acetylated Polyclonal Antibody, Biotin
Applications
- Western Blot (WB)
Tested Dilution
- 1:1,000–1:5,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Affinity-purified antibody prepared from whole rabbit serum produced by repeated immunizations with acetylated lysine conjugated KLH |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 50% glycerol, 0.15M NaCl |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Store vial at -20°C or below prior to opening.
- Dilute only prior to immediate use.
- For extended storage, aliquot contents and freeze at -20°C or below.
Target Information
In the nucleus, DNA is tightly packed into nucleosomes, creating a repressive environment for DNA processes such as transcription. Acetylation of lysine residues within proteins is an important mechanism used by cells to overcome this repression.
Acetylation of both histone and non-histone proteins, such as transcription factors, is involved in chromatin remodeling and transcriptional activation. This modification may induce structural transitions and specific signaling within chromatin domains.
Recognition of acetylated lysine by bromodomains serves as a regulatory mechanism in protein-protein interactions and intracellular signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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