Thermo Fisher Scientific RORA Polyclonal Antibody
RORA 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 사용 가능. 다양한 종에서 반응성이 높으며, 항원 친화 크로마토그래피로 정제됨. PBS 용액에 0.1% sodium azide 포함, 4°C 단기 보관 및 -20°C 장기 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 11–17 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bat, Bovine, Dog, Horse, Hamster, Human, Mouse, Non-human primate, Pig, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from hinge domain of human ROR Alpha |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551511 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig (100%).
Target Information
RORA is a receptor for retinoic acid belonging to the NR1 subfamily of nuclear hormone receptors with a nuclear receptor DNA binding domain.
RORA binds either as a monomer or as a homodimer to the retinoic acid response element and regulates gene expression and cell function.
Though the exact function of RORA is not fully known, it interacts with NM23-2, NM23-1, CDK7, NCOA3, and NCOA6 coactivators.
It is expressed in mesenchymal stem cells derived from bone marrow and modulates bone matrix components.
RORA is widely expressed in most tissues, and chromosomal aberrations involving RORA may be associated with acute promyelocytic leukemia (APL).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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