Thermo Fisher Scientific Phospho-GAP43 (Ser41) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser41 of rat GAP43 conjugated to KLH if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GAP43,uniProtId:P07936-1,ncbiNodeId:10114,antigenRange:41,antigenLength:226,antigenImageFileName:PA1-4626_GAP43_P07936-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4626_GAP43_P07936-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2263255

Product Specific Information

This antibody is predicted to react with bovine, canine, chicken, finch, human, mouse, non-human primate, Xenopus and zebrafish based on 100% sequence homology.

This antibody is specific for the ~50 kDa Gap-43 protein phosphorylated at Ser41 in Western blots of rat brain lysate. In some tissues the antibody also recognizes a higher molecular weight protein, that is also recognized by the Pan Gap-43 antibody, that may be a Gap-43 aggregate or oligomer. Immunolabeling blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide.

Target Information

GAP43 (Neuromodulin) is associated with nerve growth. GAP43 is expressed by developing and regenerating neurons, and to a lesser extent reactive glial cells. It is a major component of the motile growth cones that form the tips of elongating axons. GAP43 also plays a role in axonal and dendritic filopodia induction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.