Thermo Fisher Scientific Phospho-GAP43 (Ser41) Polyclonal Antibody
Phospho-GAP43 (Ser41) 특이적 다클론 항체로, 신경 성장 및 재생 연구에 적합. Mouse와 Rat에 반응하며 Western blot에서 50kDa GAP43 인산화 단백질 검출에 유용. Affinity chromatography로 정제된 액상 항체로 안정적 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser41 of rat GAP43 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2263255 |
Product Specific Information
This antibody is predicted to react with bovine, canine, chicken, finch, human, mouse, non-human primate, Xenopus, and zebrafish based on 100% sequence homology.
It specifically recognizes the ~50 kDa GAP43 protein phosphorylated at Ser41 in Western blots of rat brain lysate.
In some tissues, the antibody also detects a higher molecular weight protein recognized by the Pan GAP43 antibody, possibly a GAP43 aggregate or oligomer.
Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.
Target Information
GAP43 (Neuromodulin) is associated with nerve growth. It is expressed by developing and regenerating neurons, and to a lesser extent by reactive glial cells. GAP43 is a major component of the motile growth cones that form the tips of elongating axons and also plays a role in axonal and dendritic filopodia induction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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