Thermo Fisher Scientific Heat Shock 27kDa Protein 1 Monoclonal Antibody (rHSPB1/6489)
Heat shock protein HSPB1(HSP27)를 인식하는 mouse monoclonal antibody로, Western blot 및 IHC에 사용 가능. Human 반응성, Protein A/G 정제, 200 µg/mL 농도의 액상 형태. 세포 스트레스 반응 및 단백질 접힘 연구에 적합.
- 카탈로그번호
- 3315-MSM5-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Heat Shock 27kDa Protein 1 Monoclonal Antibody (rHSPB1/6489)
Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rHSPB1/6489 |
| Immunogen | Recombinant human full-length HSP27 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
In response to adverse environmental changes, cells from many organisms increase the expression of heat shock or stress proteins.
HSPB1 (heat shock protein beta-1, also known as HSP27) is a small heat shock protein functioning as a molecular chaperone that maintains denatured proteins in a folding-competent state.
It plays roles in stress resistance and actin organization. Through its chaperone activity, HSP27 regulates biological processes such as phosphorylation and axonal transport of neurofilament proteins.
Mutations in the gene can result in Charcot-Marie-Tooth disease 2F and distal hereditary motor neuronopathy 2B.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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