Thermo Fisher Scientific S6 Polyclonal Antibody
Rabbit polyclonal antibody targeting human RPS6 C-terminus region. Validated for WB and ICC/IF applications. High purity via antigen affinity chromatography. Supplied as liquid form, 0.77 mg/mL concentration, suitable for multiple species reactivity.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RPS6 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.77 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792790 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Dog (100%), Chicken (100%), Bovine (100%).
- Positive Control: HeLa, HepG2.
- Centrifuge briefly prior to opening the vial.
Target Information
Ribosomes are the organelles that catalyze protein synthesis, consisting of a small 40S subunit and a large 60S subunit. These subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.
The RPS6 gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit and belongs to the S6E family. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different kinases. Phosphorylation is induced by various stimuli such as growth factors, tumor-promoting agents, and mitogens, while dephosphorylation occurs at growth arrest.
RPS6 may contribute to the control of cell growth and proliferation through selective translation of specific mRNA classes. Multiple processed pseudogenes of this gene are dispersed throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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