Thermo Fisher Scientific MYH7 Monoclonal Antibody (TH81 (BGN/04/4481))

Applications

Tested Dilution

Publications

Western Blot (WB)

1:4,000

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunocytochemistry (ICC/IF)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Published species

Rat

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

TH81 (BGN/04/4481)

Immunogen

Myosin heavy chain from rabbit muscle. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MYH7,uniProtId:P04461-1,ncbiNodeId:9986,antigenRange:1-736,antigenLength:736,antigenImageFileName:MA1-83347_MYH7_P04461-1_House_mouse.svg,antigenImageFileNamePDP:MA1-83347_MYH7_P04461-1_House_mouse_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_936651

Product Specific Information

Mouse anti Rabbit muscle myosin heavy chain antibody, clone TH81 recognizesthe heavy chain of rabbit muscle myosin.

Target Information

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.