Thermo Fisher Scientific MYH7 Monoclonal Antibody (TH81 (BGN/04/4481))
MYH7 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. 마우스 IgG1 형이며 비결합 상태로 제공되며, 근육 마이오신 연구 및 심근병 관련 연구에 활용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:4,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TH81 (BGN/04/4481) |
| Immunogen | Myosin heavy chain from rabbit muscle |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_936651 |
Product Specific Information
Mouse anti-rabbit muscle myosin heavy chain antibody, clone TH81, recognizes the heavy chain of rabbit muscle myosin.
Target Information
Muscle myosin is a hexameric protein composed of 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits.
The MYH7 gene encodes the beta (slow) heavy chain subunit of cardiac myosin, predominantly expressed in the human ventricle and skeletal muscle rich in slow-twitch type I fibers.
Alterations in MYH7 expression correlate with cardiac contractile velocity and occur during thyroid hormone depletion or hemodynamic overloading.
Mutations are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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