Thermo Fisher Scientific GCN4 Chimeric Recombinant Rabbit Monoclonal Antibody (C11L34)
Thermo Fisher의 GCN4 키메릭 재조합 토끼 단일클론 항체(C11L34)는 효모 GCN4 전사인자에 대한 높은 특이성과 피코몰 친화도를 지닌 항체입니다. WB, ICC/IF, IP, SPR 등 다양한 분석에 사용 가능하며, HEK293 세포에서 발현된 고순도 단백질 A 정제 항체입니다.
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Applications
- Western Blot (WB): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
- Surface Plasmon Resonance (SPR): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Yeast |
| Host / Isotype | Rabbit / IgG, lambda |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | C11L34 |
| Immunogen | Biotinylated GCN4-peptide (HLENEVARLKK) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074402 |
Product Specific Information
This antibody binds to the HLENEVARLKK peptide from the leucine-zipper domain of the S. cerevisiae GCN4 transcriptional activator with picomolar affinity.
Target Information
GCN4 is a transcription factor protein in yeast that regulates genes involved in amino acid biosynthesis, including HIS4, HIS7, HIS3, ARG1, ARG3, ARG4, ARG5,6.
It contains a basic leucine zipper (bZIP) domain enabling DNA binding and transcription regulation.
GCN4 also participates in stress response and nutrient signaling pathways, such as GSH1, YAP1, TRX2.
Structurally, it consists of a dimeric coiled-coil domain for protein-protein interactions and a DNA-binding bZIP domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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