Thermo Fisher Scientific Cathepsin K Monoclonal Antibody (CTSK, 2791)
Cathepsin K 단백질을 인식하는 마우스 단클론 항체로, 인간 시료에 반응합니다. IHC(P) 및 Peptide Array에 사용 가능하며, 단백질 A/G로 정제된 액상 항체입니다. PBS(pH 7.4)에 보존되어 있으며, 방부제는 포함하지 않습니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CTSK, 2791 |
| Immunogen | Recombinant fragment of human Cathepsin K protein (around aa 163–274) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption.
It belongs to the peptidase C1 protein family and is predominantly expressed in osteoclasts.
This protein is also expressed in some human breast cancers, potentially contributing to tumor invasiveness.
Mutations in this gene cause pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
This gene may be subject to RNA editing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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