Thermo Fisher Scientific Cathepsin K Monoclonal Antibody (CTSK, 2791)
Cathepsin K 단백질을 인식하는 Mouse monoclonal antibody로, IHC(P) 및 peptide array에 사용 가능. 인간 시료 반응성. 단백질 A/G로 정제된 액상 항체이며, 4°C 보관. 골 재형성 및 종양 침습 관련 연구에 적합.
- 카탈로그번호
- 1513-MSM1-P1
- 판매단위
- pk
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Thermo Fisher Scientific Cathepsin K Monoclonal Antibody (CTSK, 2791)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CTSK, 2791 |
| Immunogen | Recombinant fragment of human Cathepsin K protein (around aa 163–274) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at room temperature for 20 min.
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption.
It is predominantly expressed in osteoclasts and also found in human breast cancers, potentially contributing to tumor invasiveness.
Mutations cause pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.
This gene may be subject to RNA editing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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