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Thermo Fisher Scientific CD40 Monoclonal Antibody (LOB7/6), PE

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CD40 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, PE 형광 표지되어 있습니다. 사람 및 개 시료에 반응하며 유세포분석(Flow Cytometry)에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 4°C에서 보관합니다.

브랜드: Thermo Fisher Scientific
카테고리: Monoclonal Antibodies
판매단위: pk

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마지막 업데이트 2025. 08. 05. 오후 09:48

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Thermo Fisher Scientific MA180928 CD40 Monoclonal Antibody (LOB7/6), PE 100 tests pk판매 단위 pk ·

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713,600원VAT 포함 784,960원

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Thermo Fisher Scientific · Thermo Fisher Scientific CD40 Monoclonal Antibody (LOB7/6), PE

Applications

Flow Cytometry (Flow): Neat

Product Specifications

항목	내용
Species Reactivity	Dog, Human
Host / Isotype	Mouse / IgG2a
Class	Monoclonal
Type	Antibody
Clone	LOB7/6
Immunogen	CD40 Ig(Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG
Conjugate	PE (R-Phycoerythrin)
Excitation / Emission Max	565 / 576 nm
Form	Lyophilized
Concentration	Not Determined
Purification	Purified
Storage Buffer	PBS, pH 7.4, with 5% sucrose, 1% BSA
Contains	0.09% sodium azide
Storage Conditions	4°C, store in dark, DO NOT FREEZE!
Shipping Conditions	Ambient (domestic); Wet ice (international)
RRID	AB_928285

Product Specific Information

Reconstitute with 1 mL of distilled water.
After reconstitution, store product undiluted at 4ºC in the dark.
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Mouse anti-Human CD40 antibody, clone LOB7/6 recognizes the human CD40 cell surface antigen, a 48 kDa glycoprotein expressed by B lymphocytes and weakly by some monocytes.

Target Information

CD40 antigen is a single-chain glycoprotein belonging to the tumor necrosis factor/nerve growth factor superfamily. It shows significant homology to the Hodgkin’s disease-associated antigen CD30. CD40 is expressed on all B cells except plasma cells and is also found on some epithelial cells, carcinomas, and lymphoid dendritic cells. It plays an essential role in immune and inflammatory responses, including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.
AKNA transcription factor regulates CD40 expression, facilitating homotypic cell interactions. TNFR2 adaptor protein interacts with CD40 to mediate signal transduction. The CD40-CD40L interaction is necessary for amyloid-beta-induced microglial activation, implicated in early Alzheimer’s disease pathogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
Diseases associated with CD40 dysfunction include Type 3 Hyper-IgM immunodeficiency and CD40 ligand deficiency.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.