Thermo Fisher Scientific Claudin 7 Polyclonal Antibody
Claudin 7 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB 및 IHC(P)에서 검증됨. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며 PBS 완충액에 안정화제 포함. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from C-terminus of human claudin 7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: HEK293
- Cellular location: Cell junction
Target Information
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier preventing solutes and water from freely passing through the paracellular space between epithelial or endothelial cells. They also play critical roles in maintaining cell polarity and signal transduction.
Differential expression of this gene has been observed in various malignancies, including breast, ovarian, liver, urinary, prostate, lung, head and neck, and thyroid cancers.
Alternatively spliced transcript variants encoding different isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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