Thermo Fisher Scientific HIF3A Polyclonal Antibody
HIF3A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western Blot에 최적화되어 있습니다. 인간 HIF-3 alpha N-말단을 면역원으로 사용하였으며, 액상 형태로 제공됩니다. 연구용으로 산소 항상성 관련 단백질 분석에 적합합니다.
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Thermo Fisher Scientific HIF3A Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Bacterially expressed human HIF-3 alpha (N-terminus) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_2117280 |
Product Specific Information
Suggested positive control: reticulocyte lysate.
Target Information
Cell growth and viability are compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors, including HIF-1 alpha, HIF-1 beta (Arnt 1), EPAS-1 (HIF-2 alpha), and HIF-3 alpha, induce glycolysis, erythropoiesis, and angiogenesis to restore oxygen homeostasis. These factors belong to the Per-Arnt-Sim (PAS) domain transcription factor family. Under hypoxic conditions, HIF-1 alpha is upregulated and forms a heterodimer with Arnt 1 to create the HIF-1 complex, which binds to the hypoxia responsive element (HRE) of target genes, activating transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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