Thermo Fisher Scientific Phospho-Synapsin 1 (Ser603) Polyclonal Antibody
Phospho-Synapsin 1 (Ser603) 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합합니다. Human, Mouse, Rat 등 다양한 종과 반응하며, 신경세포 내 시냅스 단백질 연구에 활용됩니다. 액상 형태로 제공되며, -20°C 보관이 필요합니다.
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Applications
Western Blot (WB)
- Tested dilution: 1:1,000
- View 3 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Rhesus monkey |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser603 of rat SYN1 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560615 |
Product Specific Information
This antibody is predicted to react with human, Xenopus, bovine, mouse, and zebrafish based on 100% sequence homology.
In Western blot, this antibody detects an approximately 78 kDa protein representing Phospho-Ser603 Synapsin I protein.
Target Information
SYN1 (Synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. These proteins are characterized by common domains and are implicated in synaptogenesis and neurotransmitter release modulation, suggesting a role in neuropsychiatric diseases.
Synapsin 1 regulates axonogenesis and synaptogenesis, serving as a substrate for multiple kinases. Phosphorylation may regulate its function in nerve terminals. Mutations in this gene may be linked to X-linked neuronal degeneration disorders such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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