Thermo Fisher Scientific mGluR2/mGluR3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

1:10-1:500

-

Product Specifications

Species Reactivity

Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Residues 860-872 of the rat mGlurR2/3 protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:mGluR2/mGluR3,uniProtId:P31421-1,ncbiNodeId:10114,antigenRange:860-872,antigenLength:872,antigenImageFileName:PA1-46113_mGluR2mGluR3_P31421-1_Rabbit.svg,antigenImageFileNamePDP:PA1-46113_mGluR2mGluR3_P31421-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:mGluR2/mGluR3,uniProtId:P31422-1,ncbiNodeId:10114,antigenRange:860-872,antigenLength:879,antigenImageFileName:PA1-46113_mGluR2mGluR3_P31422-1_Rabbit.svg,antigenImageFileNamePDP:PA1-46113_mGluR2mGluR3_P31422-1_Rabbit_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2115903

Product Specific Information

This antibody is predicted react to human and mouse based on sequence homology.

Target Information

The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.