Thermo Fisher Scientific IL-2 Recombinant Rabbit Monoclonal Antibody (5M4Y3)
IL-2 인간 단백질을 인식하는 토끼 재조합 단클론 항체로, WB, Flow Cytometry, ELISA에 사용 가능. HEK293 발현 시스템에서 생산되며, 높은 순도와 안정성 제공. 연구용으로 면역 반응 및 세포 활성화 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5M4Y3 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–153 of human IL-2 (NP_000577.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2911889 |
Product Specific Information
Positive test controls include: 293T, Jurkat.
The target is usually found in the following locations: Secreted.
Immunogen sequence:
MYRMQLLSCI ALSLALVTNS APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFCQSIIS TLT
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by IL-4 and IL-7.
The expression of the IL-2 gene in mature thymocytes is monoallelic, representing an unusual regulatory mode for controlling precise expression of a single gene.
Targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease, suggesting an essential role in immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: MA5-42748_IL-2_P60568-1_Rabbit.svg, MA5-42748_IL-2_P60568-1_Rabbit_PDP.jpeg)
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