Thermo Fisher Scientific IL-2 Recombinant Rabbit Monoclonal Antibody (5M4Y3)
IL-2 인간 단백질을 인식하는 토끼 재조합 단클론 항체로, WB, Flow Cytometry, ELISA에 사용 가능. HEK293 발현 시스템에서 생산되며, 높은 순도와 안정성 제공. 연구용으로 면역 반응 및 세포 활성화 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5M4Y3 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–153 of human IL-2 (NP_000577.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2911889 |
Product Specific Information
Positive test controls include: 293T, Jurkat.
The target is usually found in the following locations: Secreted.
Immunogen sequence:
MYRMQLLSCI ALSLALVTNS APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFCQSIIS TLT
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by IL-4 and IL-7.
The expression of the IL-2 gene in mature thymocytes is monoallelic, representing an unusual regulatory mode for controlling precise expression of a single gene.
Targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease, suggesting an essential role in immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: MA5-42748_IL-2_P60568-1_Rabbit.svg, MA5-42748_IL-2_P60568-1_Rabbit_PDP.jpeg)
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