
Thermo Fisher Scientific GRIP1 Polyclonal Antibody
Thermo Fisher Scientific GRIP1 Polyclonal Antibody는 인간 GRIP1 단백질(725–775 잔기 영역)을 인식하는 토끼 IgG 항체입니다. Western blot 및 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 725 to 775 of human Glutamate Receptor Interacting Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Steroid and thyroid hormones and retinoic acid regulate gene expression via intracellular receptor transcription factors of the ligand-dependent nuclear receptor superfamily. Coactivators and corepressors modulate transcriptional activity of these receptors.
Glucocorticoid receptor interacting protein-1 (GRIP1), also known as Transcription Intermediary Factor 2 (TIF2), is a coactivator protein related to SRC-1 and AIB-1. GRIP1 interacts with multiple receptors, including retinoic acid, retinoid X, vitamin D, mineralocorticoid, glucocorticoid, thyroid hormone, androgen, estrogen, progesterone, and PPARs.
It contains conserved LXXLL/LLXXL motifs essential for receptor–coactivator interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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