Thermo Fisher Scientific GRIP1 Polyclonal Antibody
GRIP1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot과 Immunoprecipitation에 적합. Human에 반응하며 Mouse, Rat에서도 예측 반응. 항원 친화 크로마토그래피로 정제되고 4°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1026 to 1076 of human Glutamate Receptor Interacting Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
Steroid, thyroid hormones, and retinoic acid regulate gene expression via intracellular receptor transcription factors of the ligand-dependent nuclear receptor superfamily. Coactivators and corepressors modulate transcriptional activity of these receptors.
Glucocorticoid receptor interacting protein-1 (GRIP1), also known as Transcription Intermediary Factor 2 (TIF2), is a member of the transcriptional coactivator family that includes SRC-1 and AIB-1. GRIP1 interacts with and enhances transcriptional activity of receptors for retinoic acid, retinoid X, vitamin D, mineralocorticoid, glucocorticoid, thyroid hormone, androgen, estrogen, progesterone, and PPARs.
It contains multiple LXXLL/LLXXL motifs critical for receptor–coactivator interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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