Thermo Fisher Scientific GRIP1 Polyclonal Antibody
Rabbit polyclonal antibody against human GRIP1 (Glutamate Receptor Interacting Protein 1). Validated for WB and IP applications. Predicted cross-reactivity with mouse and rat. Supplied as 1 mg/mL liquid, stored at 4°C. For research use only.
- 카탈로그번호
- A304004Ax (2개 옵션)
- 판매단위
- pk
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GRIP1 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1026 to 1076 of human Glutamate Receptor Interacting Protein 1 (GRIP1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily.
Coactivators and corepressors modulate transcriptional activity of these nuclear receptors.
Glucocorticoid receptor interacting protein-1 (GRIP1), also known as Transcription Intermediary Factor 2 (TIF2), is part of a transcriptional coactivator family that includes SRC-1 and AIB-1.
GRIP1 interacts with and stimulates the transcriptional activity of retinoic acid, retinoid X, vitamin D, mineralocorticoid, glucocorticoid, thyroid hormone, androgen, estrogen, progesterone, and peroxisome proliferator-activated receptors.
It contains multiple conserved LXXLL/LLXXL motifs critical for receptor–coactivator interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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