Thermo Fisher Scientific CD4 Monoclonal Antibody (KEN-4)

Applications

Product Specifications

Additional Formats:

• FITC Conjugate
• Request Custom Conjugation

Product Specific Information

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.

Mouse anti-Rabbit CD4 antibody, clone KEN-4 recognizes the rabbit CD4 cell surface antigen, a 50 kDa glycoprotein expressed by T helper cells.
This antibody blocks the allogeneic mixed lymphocyte reaction response.

Target Information

The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV.
CD4 is primarily expressed in T helper cells but may also be found in monocytes, macrophages, and dendritic cells.
Tissue expression includes thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut.
CD4 functions to initiate or augment early T-cell activation via association with the T-cell receptor complex and protein tyrosine kinase Lck.
It may also mediate neuronal damage in infectious and immune-mediated diseases of the CNS.
Multiple alternatively spliced transcripts have been identified in this gene (RefSeq, July 2017).

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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