Thermo Fisher Scientific MHC I polymorphic Monoclonal Antibody (ER-MP42)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Clone ER-MP42 specifically recognizes mouse strains with the haplotypes H-2Kv, H-2Dd, and H-2k, q, s.
Mouse strains with haplotypes H-2p, r, w7, w22 show weak reactivity with this antibody.

For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.

Target Information

The major histocompatibility complex (MHC) is a cluster of genes important in the immune response to infections.
In mice, this complex is referred to as the histocompatibility 2 (H-2) region.
The polymorphic epitope is present on murine MHC class I molecules, which are expressed at varying levels on the majority of nucleated cells.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.

For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.