Thermo Fisher Scientific PSMD2 Monoclonal Antibody (OTI1B4), TrueMAB
인간 PSMD2 단백질을 인식하는 단클론 항체로 Western blot 및 Immunocytochemistry에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 안정적인 저장 용액을 포함합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B4 |
| Immunogen | Full length human recombinant protein of human PSMD2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes, a 20S core and a 19S regulator.
The 20S core consists of four rings of 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits).
The 19S regulator includes a base with six ATPase and two non-ATPase subunits, and a lid containing up to ten non-ATPase subunits.
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent process via a non-lysosomal pathway.
The immunoproteasome plays an essential role in processing class I MHC peptides.
This gene encodes one of the non-ATPase subunits of the 19S regulator lid and may also participate in the TNF signaling pathway through interaction with the TNF type 1 receptor.
A pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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