Thermo Fisher Scientific NBN Monoclonal Antibody (OTI6A3), TrueMAB
인간 NBN 단백질(aa 183-460)에 특이적인 단클론 항체로 Western blot에 최적화됨. Mouse IgG1 아이소타입이며, 동결건조 형태로 제공. PBS(8% 트레할로스 포함)에 용해 가능하며, 재구성 후 약 1 mg/mL 농도로 사용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 183-460 of human NBN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The p95 gene (also known as NBS1 or nibrin) is a component of the hMre11/hRad50 double-strand break repair complex.
This complex is associated with Nijmegen breakage syndrome, an autosomal recessive disorder characterized by increased cancer susceptibility, cell cycle checkpoint defects, and sensitivity to ionizing radiation, linking double-strand break repair to cell cycle regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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