Thermo Fisher Scientific NBN Monoclonal Antibody (OTI3G3), TrueMAB
인간 NBN 단백질(aa 183-460)을 항원으로 한 Mouse IgG1 단클론 항체. Western blot에 1:2,000 희석으로 사용 가능. 동결건조 형태로 제공되며 PBS buffer에 8% trehalose 포함. 연구용으로만 사용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 183–460 of human NBN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The p95 gene (identical to NBS1 and nibrin) is part of the hMre11/hRad50 double-strand break repair complex. This complex is associated with Nijmegen breakage syndrome, an autosomal recessive disorder characterized by increased cancer risk, cell cycle checkpoint defects, and ionizing radiation sensitivity — linking double-strand break repair and cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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