Thermo Fisher Scientific MCP-1 Monoclonal Antibody (2D8)
CCL2 단백질을 인식하는 Thermo Fisher Scientific의 MCP-1 Monoclonal Antibody (Clone 2D8). Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 적합. Human, Mouse, Non-human primate 반응성. Protein G 정제, 1 mg/mL 농도, 장기 보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 7 publications |
| Immunohistochemistry (IHC) | - | View 11 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 | View 4 publications |
| Flow Cytometry (Flow) | 1:200–1:400 | View 2 publications |
| ELISA | 1:10,000 | View 1 publication |
| Neutralization (Neu) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D8 |
| Immunogen | Purified recombinant fragment of human CCL2 expressed in E. Coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538512 |
Product Specific Information
MA5-17040 targets CCL2 in indirect ELISA, FACS, ICC, IHC, IF, and WB applications and shows reactivity with Human, Mouse, and Non-human primate samples.
The MA5-17040 immunogen is a purified recombinant fragment of human CCL2 expressed in E. coli.
MA5-17040 detects CCL2, which has a predicted molecular weight of approximately 11 kDa.
Target Information
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are secreted proteins involved in immunoregulatory and inflammatory processes.
The encoded protein is structurally related to the CXC subfamily of cytokines, characterized by two cysteines separated by a single amino acid.
This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils, and is implicated in diseases with monocytic infiltrates such as psoriasis, rheumatoid arthritis, and atherosclerosis.
It binds to chemokine receptors CCR2 and CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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