Thermo Fisher Scientific KRT5 Monoclonal Antibody (OTI1F8), TrueMAB

Thermo Fisher Scientific KRT5 Monoclonal Antibody (OTI1F8), TrueMAB

Applications

• Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150

Product Specifications

Product Specific Information

Synthetic peptide sequence:
EQGTKTVRQN LEPLFEQYIN NLRRQ

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Cytokeratin pan belongs to a subfamily of intermediate filament proteins with significant biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides.
Cytokeratins range in molecular weight from 40–68 kDa and have an isoelectric pH between 4.9–7.8.
Their expression patterns are characteristic of epithelial type and differentiation stage, aiding in distinguishing epithelial malignancies.
Cytokeratin antibodies are valuable for differential tumor diagnosis via immunohistochemistry, cytopathology, and flow cytometry assays.
Keratin expression varies with cell type, differentiation, growth environment, and disease state, making keratins useful markers in cancer research and tumor diagnostics.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.