Thermo Fisher Scientific KRT5 Monoclonal Antibody (OTI1F8), TrueMAB
인간 KRT5 단백질을 인식하는 Mouse IgG1 단클론 항체로, IHC(P)에서 1:150 희석으로 검증됨. 합성 펩타이드 면역원 기반, 보존제 무첨가. 세포분화 및 종양 진단 연구용으로 적합. -20°C 보관, 동결·해동 반복 회피.
- 카탈로그번호
- CF800714
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific KRT5 Monoclonal Antibody (OTI1F8), TrueMAB
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F8 |
| Immunogen | Synthetic peptide sequence corresponding to the conserved region of human KRT5 and KRT6 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Synthetic peptide sequence:
EQGTKTVRQN LEPLFEQYIN NLRRQ
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Cytokeratin pan belongs to a subfamily of intermediate filament proteins with significant biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides.
Cytokeratins range in molecular weight from 40–68 kDa and have an isoelectric pH between 4.9–7.8.
Their expression patterns are characteristic of epithelial type and differentiation stage, aiding in distinguishing epithelial malignancies.
Cytokeratin antibodies are valuable for differential tumor diagnosis via immunohistochemistry, cytopathology, and flow cytometry assays.
Keratin expression varies with cell type, differentiation, growth environment, and disease state, making keratins useful markers in cancer research and tumor diagnostics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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