Thermo Fisher Scientific Phospho-C/EBP epsilon (Thr74) Polyclonal Antibody
Human C/EBP epsilon 인산화 부위(Thr74)를 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. 1 mg/mL 농도의 액상 형태이며 PBS/glycerol 버퍼에 보관. HUVEC 세포를 양성 대조로 사용 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Suggested Positive Control: HUVEC cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of threonine 174 (L-A-T(p)-A-A) derived from Human C/EBP-epsilon |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554131 |
Target Information
C/EBP alpha regulates gene expression in a variety of tissues including liver, adipose, lung, and intestine.
C/EBP alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through amphipathic alpha helices termed the leucine zipper.
Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces.
C/EBP alpha functions exclusively in terminally-differentiated, growth-arrested cells.
Additional family members include C/EBP beta, C/EBP gamma, C/EBP delta, and C/EBP epsilon, all exhibiting similar DNA-binding specificities and affinities to C/EBP alpha.
C/EBP beta and C/EBP delta readily form heterodimers both with each other and with C/EBP alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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