Thermo Fisher Scientific Tryptase Monoclonal Antibody (TPSAB1, 1961)
인간 Tryptase 단백질을 인식하는 mouse monoclonal 항체로, IHC(P) 및 Peptide Array에 사용 가능. 고순도 Protein A/G 정제, PBS buffer에 보존. 염증 및 면역 반응 연구에 적합하며 연구용으로만 사용.
- 카탈로그번호
- 7177-MSM1-P1ABX
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- pk
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Thermo Fisher Scientific Tryptase Monoclonal Antibody (TPSAB1, 1961)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TPSAB1, 1961 |
| Immunogen | Recombinant human Tryptase protein fragment (around aa 115–233) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C followed by cooling at room temperature for 20 minutes.
Target Information
Tryptase is a serine protease primarily found in mast cells, playing a crucial role in the immune response by cleaving and activating proteins involved in inflammation and tissue repair.
It also participates in blood pressure regulation and is implicated in diseases such as asthma, allergies, and cardiovascular disorders.
Tryptase consists of four identical subunits forming a tetramer and is activated by proteolytic cleavage of its proenzyme form.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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