Thermo Fisher Scientific Tryptase (Mast Cell Marker) Monoclonal Antibody (TPSAB1/1963)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

TPSAB1/1963

Immunogen

Recombinant human Tryptase protein fragment (around aa 115-233). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Tryptase,uniProtId:Q15661-1,ncbiNodeId:9606,antigenRange:115-233,antigenLength:275,antigenImageFileName:7177-MSM3-P1ABX_Tryptase_Q15661-1_House_mouse.svg,antigenImageFileNamePDP:7177-MSM3-P1ABX_Tryptase_Q15661-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Tryptase is a protein that belongs to the family of serine proteases and is primarily found in mast cells. It plays a crucial role in the immune response by cleaving and activating other proteins involved in inflammation and tissue repair. Tryptase is also involved in the regulation of blood pressure and has been implicated in various diseases, including asthma, allergies, and cardiovascular disorders. Its structure consists of four identical subunits that form a tetramer, and it is activated by proteolytic cleavage of its proenzyme form.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.