Thermo Fisher Scientific Tryptase Monoclonal Antibody (TPSAB1, 1961)
인간 Tryptase 단백질을 표적으로 하는 TPSAB1, 1961 클론의 Mouse Monoclonal Antibody. IHC(P) 및 Peptide Array에 사용 가능. 200 µg/mL 농도의 액상 제품으로, PBS/BSA 버퍼에 보존. 염증 및 면역 연구에 적합.
- 카탈로그번호
- 7177-MSM1-P0
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Thermo Fisher Scientific Tryptase Monoclonal Antibody (TPSAB1, 1961)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | TPSAB1, 1961 |
| Immunogen | Recombinant human Tryptase protein fragment (around aa 115–233) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Tryptase is a serine protease primarily found in mast cells. It plays a key role in immune response by cleaving and activating proteins involved in inflammation and tissue repair.
It also contributes to blood pressure regulation and is associated with conditions such as asthma, allergies, and cardiovascular disorders.
Tryptase forms a tetramer structure composed of four identical subunits and is activated by proteolytic cleavage of its proenzyme form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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